Faculty A-Z | Faculty of Medicine | Memorial University of Newfoundland

Bruce Van Vliet

Professor of Cardiovascular/Renal Physiology B.Sc. Toronto, Ph.D. Saskatchewan

BioMedical Sciences

Phone:
709-864-4929

Email:
vanvliet@mun.ca

Address:
Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland Room: 4350, HSC

Dr. Van Vliet is interested in cardiovascular control mechanisms and, in particular, the regulation of blood pressure. His areas of investigation have included comparative physiology of the cardiovascular and respiratory systems, baroreceptors and baroreflexes, blood pressure variability, obesity, and autonomic mechanisms.

Dr. Van Vliet's current interests include the mathematical modeling and analysis of the ability of the cardiac baroreflex to sustain the balance between left ventricular oxygen supply and demand during changes in systolic arterial pressure.

Dr. Van Vliet's research has been supported by the Canadian Institutes of Health Research (CIHR), Heart and Stroke Foundation, Memorial University of Newfoundland (MUN), Memorial University’s Medical Research Endowment Fund (MRF), and the Province of Newfoundland and Labrador.

People associated with the Van Vliet laboratory

Linda Chafe (Research Assistant)
Dr. Graham Fraser (Cardio-Renal Research Group and Graduate Program).
Dr. Dake Qi (Cardio-Renal Research Group and Graduate Program).
Dr. John Smeda (Cardio-Renal Research Group and Graduate Program).
Dr. Bruno Stuyvers (Cardio-Renal Research Group and Graduate Program).
Dr. Reza Tabrizchi (Cardio-Renal Research Group and Graduate Program).
Dr. Sudesh Vasdev (Cardio-Renal Research Group and Graduate Program).

Selected Publications:

Myrie SB, McKnight LL, King JC, McGuire JJ, Van Vliet BN, Cheema SK, Bertolo RF. Intrauterine growth-restricted Yucatan miniature pigs experience early catch-up growth, leading to greater adiposity and impaired lipid metabolism as young adults. Appl Physiol Nutr Metab. 2017 Dec;42(12):1322-1329.

Arsenijevic D, Cajot JF, Fellay B, Dulloo AG, Van Vliet BN, Montani JP. Uninephrectomy-Induced Lipolysis and Low-Grade Inflammation Are Mimicked by Unilateral Renal Denervation. Front Physiol. 2016 Jun 14;7:227.

Kolypetri P, Randell E, Van Vliet BN, Carayanniotis G. High salt intake does not exacerbate murine autoimmune thyroiditis. Clin Exp Immunol. 2014 Jun; 176(3):336-40.

Van Vliet BN, Campbell NR. Canadian Hypertension Education Program. Efforts to reduce sodium intake in Canada: why, what, and when? Can J Cardiol. 2011 Jul-Aug; 27(4):437-45.

McLoone V, Ringwood J, Van Vliet B. A 5-component mathematical model for salt-induced hypertension in Dahl-S and Dahl-R rats. Comput Methods Programs Biomed. 2011 Feb; 101:220-9.

Mangourova V, Ringwood J, Van Vliet B. Graphical simulation environments for modelling and simulation of integrative physiology. Comput Methods Programs Biomed. Computer Methods and Programs in Biomedicine 2011 June; 102: 295-304

Montani JP, Van Vliet BN. Understanding the contribution of Guyton's large circulatory model to long-term control of arterial pressure. Exp Physiol. 2009 Apr; 94(4):382-8.

McCormick D, Budgett DM, Lim MK, Van Vliet B, Nielsen PF, Hu AP, Malpas SC. Frequency response of implantable blood pressure telemetry systems. Clin Exp Pharmacol Physiol. 2010 Aug; 37(8):862-9.

Vukolic A, Antic V, Van Vliet BN, Yang Z, Albrecht U, Montani JP. Role of mutation of the circadian clock gene Per2 in cardiovascular circadian rhythms. Am J Physiol Regul Integr Comp Physiol. 2010 Mar; 298(3):R627-34.

McCloone VI, Ringwood JV, Van Vliet BN. A multi-component model of the dynamics of salt-induced hypertension in Dahl-S rats. BMC Physiol. 2009 Oct 29;9(1):20.

Van Vliet BN, Montani J-P. The Time Course of Salt-Induced Hypertension and Why it Matters. Int J Obesity. 2008; 32:S35-S47.

Van Vliet BN, Guild S-J, Barrett C, McBryde F, Malpas S. Long-term recording of renal sympathetic nerve activity in conscious rats by telemetry. Experimental Biology 2008. FASEB J: 22:738.10.

Van Vliet BN, Chafe LL. Effect of maternal eNOS genotype on blood pressure and activity in mice. Hypertension. 2007; Mar; 49(3):556-62.

Montani JP and VanVliet BN. Integrative Renal Regulation of Sodium Excretion. In: Sodium in Health and Disease. Michel Burnier (Ed). CRC Press, 2007.

Van Vliet BN, Chafe LL, Halfyard S, Leonard AM. Distinct rapid and slow phases of salt-induced hypertension in Dahl salt-sensitive rats. J Hypertension 24:1599-1606, 2006.

Leonard AM, Chafe LL, Montani J-P, Van Vliet BN. Increased salt-sensitivity in eNOS knockout mice. Am J Hypertens. 2006 Dec; 19(12):1264-9.

Van Vliet BN, Chafe LL, Leonard AM, Joshi A, Montani J-P. Phenotying mouse blood pressure by telemetry. Clin Exp Pharm Physiol 2006; 33: 1007 - 1015.

Van Vliet BN and Montani JP. Circulation and Fluid Volume Control. In: Integrative Physiology. Humana Press, 2005.

Van Vliet BN, LL Chafe, J-P Montani. Characteristics of 24 h telemetered blood pressure in eNOS knockout and C57Bl/6J control mice. J Physiol (London) 549.1: 313 – 325, 2003.

Van Vliet B.N, Kiener-Belforti F, Montani J-P. Baroreflex stabilization of the double (pressure-rate) product at 0.05 Hz in conscious rabbits. Am J Physiol Regulatory Integrative and Comparative Physiology 282: R1746 - 1753, 2002.

Van Vliet BN, Chafe LL, Antic V, Schnyder-Candrian S, Montani J-P. Direct and indirect methods used to study arterial blood pressure. J Pharm Toxicol Methods 44: 361 - 373, 2000.

Van Vliet, B.N., L.L. Chafe, and J.P. Montani. Contribution of baroreceptors and chemoreceptors to ventricular hypertrophy produced by sino-aortic denervation in rats. J Physiol (London) 516: 885 - 895, 1999.

Van Vliet, B.N. and J.P. Montani. Baroreflex stabilization of the double product. Am J Physiol: Am J Physiol 277: H1679 - H1689, 1999.

Van Vliet, B.N., and N.H. West. Phylogenetic trends in the baroreceptor control of arterial blood pressure. Physiol Zool 67: 1284 - 1304, 1994.