Faculty A-Z
John Harnett
Professor of Medicine (Nephrology) M.B., B.Ch., B.A.O. Cork, F.R.C.P.I., FRCPCMedicine Nephrology
What brought me to MUN? What keeps me at MUN?
I initially came to Memorial in 1985 as the first resident in the newly accredited nephrology training program. The quality of that program and the expertise of the faculty exceeded my highest expectations. I was privileged to receive a McLaughlin Fellowship to pursue graduate studies in Clinical Epidemiology at McMaster University with a view to returning as Assistant Professor of Medicine which I did in 1989. The nurturing, support and mentorship I received as a resident and junior faculty member was outstanding and definitely gave me a strong commitment to the Faculty of Medicine I was provided with the opportunity to pursue local and national academic leadership positions which I don’t think would been available in larger centres.
I have always appreciated the collegiality that exists in our clinical disciplines within the faculty of medicine. Similarly the opportunity to interact with colleagues in Biomedical Sciences and Community Health and Humanities has been enriching and uniquely possible given the matrix structure of the medical school.
The experience of living and raising a family in St. John’s has been a wonderful experience
| Education: | Crescent College, Limerick, Ireland 1969- 1975 MB, BCh, BAO, (Hons.), 1981, University College Cork (1st place in class) |
| Training: | |
| Internal Medicine | Cork Regional Hospital, Cork Ireland July 1, 19811 - June 30, 1985 |
| Nephrology and Clinical Research | Health Sciences Centre, Memorial University. St. John's, NL July 1985 - December 1988 |
| Clinical Epidemiology | McMaster University, Hamilton ON July 1988 - June 1989 |
| Teaching: | I have been extensively involved over many years in undergraduate, postgraduate and graduate teaching I have supervised numerous graduate students. |
| Administrative Commitments | |
| Chief | Division of Nephrology The General Hospital Health Sciences Centre St. John’s, Newfoundland June 1993 - December 1995 |
| Acting Chair | Discipline of Medicine Memorial University of Newfoundland Health Sciences Centre St. John’s, Newfoundland January 1996 - August 1996 |
| Chair | Discipline of Medicine Memorial University of Newfoundland September 1, 1996 – August 31st 2002 |
| HSC Site Clinical Chief | September 1, 1996 – August 31st 2000 |
| Clinical Chief | September 1, 2000 – August 31st 2002 Medicine Program Health Care Corporation of St. John’s |
| Research Ethics Review | |
| 1989 - 1993 | Chair, Human Investigation Committee (HIC) |
| 1996 – 2003 | Chair, HIC Appeals Committee |
| 2003 – 2010 | Co-Chair Human Investigation Committee |
Kidney Foundation of Canada
| 1996-1999 | Member, Scholarship and Fellowship Committee |
| 1999-2002 | Chair, Scholarship and Fellowship Committee |
| 2002-2006 | Co-Chair, Research Council |
| 2002-2006 | Member, Public Policy Committee |
| 2002-2006 | Member, National Board of Directors |
| 2008 | National Vice-President |
Canadian Society of Clinical Investigation
| 1999-2003 | Member of Council |
| 2000-2003 | Chair of National Awards Committee |
Canadian Institutes for Health Research (CIHR)
| 2003-2009 | Member and ethics designate of the Institute Advisory Board of the Institute of Nutrition, Metabolism and Diabetes |
Chair Horizons 2015 Planning Conference
| 2007 | Chair of Horizons 2015, a strategic planning conference to plan a 10 year strategy for kidney research in Canada, jointly sponsored by CIHR, The Kidney Foundation of Canada and the Canadian Society of Nephrology |
Awards:
| McLaughlin Fellowship | To attend MSc Program in Design, Measurement and Evaluation in the Department of Clinical Epidemiology and Biostatistics at McMaster University July 1988 – June 1989 |
| KFOC Scholarship | Awarded for research proposal entitled "Cardiac and Vascular Disease in Dialysis Patients" - $90,000 - July 1990 - June 1992 |
| ASN Travel Grant | Travel to the 1993 International Society of Nephrology meeting in Jerusalem, Israel - $1,250 |
| Outstanding Teacher | Awarded for excellence in teaching third year medical studies in the academic year 1996-1997 by the Class of 1998. |
| ACP Laureate Award | American College of Physicians in recognition of outstanding service, awarded June 2005 |
| John B Dossetor Award | Awarded in June 2006 at annual meeting of Kidney Foundation of Canada in Vancouver, B.C. for outstanding contributions to the research mission of the Kidney Foundation of Canada |
Undergraduate awards
| Blayney Prize | Awarded to the student who obtains first place in MB BCh Degree - 1981 |
| O’Donovan Prize | Awarded to the student who obtains first place in Clinical Medicine - 1981 |
| Pearson Medal | Awarded to the student who obtains first place in Clinical Surgery – 1981 |
| Fitzpatrick Prize | Awarded to the student who obtains first place in Social and Preventative Medicine - 1981 |
Publications:
1. Parfrey PS, Harnett JD, Griffiths SM, Barre PE, Guttmann RD. Cardiac disease in diabetic patients with endstage renal disease. Transplantation Proceedings 1986; 18(6): 1705-1708.
2. Harnett JD, Parfrey PS, Paul MD, Gault MH. Erythromycin - Cyclosporin interaction in renal transplant patients. Transplantation 1987; 43(2): 316-318.
3. Parfrey PS, Harnett JD, Griffiths SM, Gault MH, Barre PE, Guttmann RD. Low output left ventricular failure in endstage renal disease. American Journal of Nephrology 1987; 7: 184-191.
4. Harnett JD, Parfrey PS, Griffiths SM, Devlin WH, Guttmann RD. Clinical and echocardiographic heart disease in transplant recipients. Transplantation Proceedings, 1987; 19(4): 3415-3418.
5. Parfrey PS, Vavasour HM, Bullock M, Henry S, Harnett JD, Gault MH. Symptoms in dialysis and transplant patients. Transplantation Proceedings 1987; 19 (4), 3407-3409.
6. Harnett JD, Parfrey PS, Kennedy M, Zeldis JB, Steinmann TI, Guttmann RD. Hepatitis B disease in dialysis and transplant patients further epidemiologic and serologic studies. Transplantation 1987; 44(3): 369-376.
7. Harnett JD, Gill D, Corbett L, Parfrey PS, Gault MH. Recurrent haemoperitoneum in women on CAPD. Annals of Internal Medicine 1987; 107: 341-343.
8. Paul MD, Parfrey PS, Harnett JD, Arbus G, Cohen A, Dancey J, Gault MH. Renal transplantation in primary hyperoxaluria/oxalosis: a report of two cases. Transplantation Proceedings 1987; 19(4): 3431-3442.
9. Harnett JD, Parfrey PS, Gault MH, Barre PE, Guttmann RD. Left ventricular hypertrophy in endstage renal disease. Nephron 1988; 48: 107-115.
10. Harnett JD, Parfrey PS, Kennedy M, Zeldis JB, Steinmann TI. The long-term outcome of hepatitis B disease in haemodialysis patients. American Journal of Kidney Diseases 1988; 11(3): 210-213.
11. Parfrey PS, Harnett JD, Griffiths SM, Barre PE, Gault MH. Congestive heart failure in dialysis patients. Archives of Internal Medicine 1988; 148(7): 1519-1525.
12. Devlin WH, Harnett JD, Parfrey PS, Griffiths SM, Gault MH, Guttmann RD. The relationship between hypertension and left ventricular hypertrophy in renal transplant recipients. Transplantation Proceedings 1988; 20(6): 1221-1224.
13. Harnett JD, Green JS, Cramer BC, Johnson GJ, McManamon PJ, Farid NR, Pryse-Phillips WEM, Parfrey PS. The spectrum of renal disease in Laurence-Moon-Biedl syndrome. New England Journal of Medicine 1988; 319(10): 615-618 .
14. Cramer BC, Green JS, Harnett JD, Johnson GJ, McManamon PJ, Farid NR, Pryse-Phillips WEM, Parfrey PS. Sonographic and urographic correlation in Bardet-Biedl syndrome (formerly Laurence-Moon-Biedl syndrome). Urology Radiology 1988; 10: 176-180.
15. Green JS, Parfrey PS, Harnett JD, Cramer BC, Farid NR, Heath O, McManamon PJ, O’Leary E, Pryse- Phillips WEM. The cardinal manifestations of Bardet-Biedl syndrome (formerly Laurence-Moon-Biedl syndrome). New England Journal of Medicine 1989; 321(15): 1002-1009.
16. Barrett BJ, Harnett JD. Investigation and management of renal stones. Canadian Family Physician 1989; 35: 2095-2172.
17. Parfrey PS, Harnett JD, Griffiths SM, Taylor R, Hand J, King A, Barre PE. The clinical course of left ventricular hypertrophy in dialysis patients. Nephron 1990; 55: 114-120.
18. Parfrey PS, Griffiths SM, Harnett JD, Taylor R, King A, Hand J, Barre PE. Outcome of congestive heart failure, dilated cardiomyopathy, hypertrophic hyperkinetic disease and ischaemic heart disease in dialysis patients. American Journal of Nephrology 1990; 10: 213-221.
19. Parfrey PS, Harnett JD. The natural history of myocardial disease in dialysis patients. Journal of the American Society of Nephrology 1991; 2: 2-12.
20. Gault HM, Chafe LL, Morgan JM, Parfrey PS, Harnett JD, Walsh EA, Prabhakran VM, Dow D, Colpitts A. Comparison of patients with idiopathic calcium phosphate and calcium oxalate stones. Medicine 1991; 70: 345-359.
21. Harnett JD, Barrett BJ. How to treat renal colic and renal stones. Medicine North America 1991; 4(26): 3453- 3456.
22. Foley RN, Parfrey PS, Harnett JD. The natural history of left ventricular hypertrophy in dialysis patients. Seminars in Dialysis 1992; 5(1): 34-41.
23. Gault MH, Longerich L, Harnett JD, Wesolowski C. Predicting glomerular function from adjusted serum Nephron (Editorial) 1992; 62(3): 249-256.
24. Harnett JD, Murphy B, Collingwood P, Purchase L, Kent GM. The reliability and validity of echocardiographic measurement of left ventricular mass in haemodialysis patients. Nephron 1993; 65: 212-214.
25. Parfrey PS, Gardner E, Vavasour HM, Harnett JD, McManamon C., McDonald J, Dawe J. The feasibility and efficacy of early discharge planning initiated by the admitting department in two acute care hospitals. Clinical and Investigative Medicine 1993; 17: 88-96.
26. Harnett JD, Le H. Cardiovascular effects of erythropoietin. Dialysis and Transplantation 1993; 22(9): 536-540.
27. Harnett JD, Kent GM, Barre PE, Taylor R, Parfrey PS. Risk factors for left ventricular hypertrophy in a prospectively followed cohort of dialysis patients. Journal of the American Society of Nephrology 1994; 4(7): 1486-1490.
28. Parfrey PS, Harnett JD. The management of cardiac disease in chronic uraemia. Current Opinion in Nephrology and Hypertension 1994; 3: 145-154.
29. Harnett JD, Parfrey PS. Cardiac disease in uraemia. Seminars in Nephrology 1994; 14(3): 245-252.
30. Parfrey PS, Harnett JD. Long-term cardiac morbidity and mortality during dialysis therapy. Advances in Nephrology 1994; 23: 311-330.
31. Parfrey PS, Harnett JD. Clinical aspects of cardiomyopathy in dialysis patients. Blood Purification 1994; 12: 267-276.
32. Parfrey PS, Harnett JD. Clinical epidemiology and pathophysiology of cardiac disease in chronic uraemia. Journal of the American Society of Artificial Internal Organs 1994; 40(2): 121-129.
33. Harnett JD, Foley RN, Kent GM, Murray DC, Parfrey PS. Congestive heart failure in dialysis patients: prevalence, incidence, prognosis and risk factors. Kidney International 1995; 47: 884-890.
34. Foley RN, Parfrey PS, Harnett JD, Kent GM, Martin CJ, Murray DC, Barre PE. Clinical and echocardiographic disease in patients starting endstage renal disease therapy. Kidney International 1995; 47: 186-192.
35. Parfrey PS, Harnett JD. Heart failure and ischaemic heart disease in chronic uraemia. Current Opinion in Nephrology and Hypertension 1995; 4: 105-110. (Review)
36. Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE. Left ventricular geometry: a critical prognostic variable in ESRD patients. Journal of the American Society of Nephrology 1995; 5: 2024-2031.
37. Harnett JD, Foley RN, Kent GM, Parfrey PS. Cardiac disease and haematocrit level. American Journal of Kidney Diseases 1995; 25: 53-57.
38. Gault MH, Longerich LL, Purchase L, Harnett JD, Breckenridge C. Comparison of Lp(a) concentrations and some potential effects in haemodialysis, CAPD, transplantation, and control groups, and review of the literature. Nephron 1995; 70: 155 -170.
39. Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE. Hypoalbuminaemia, cardiac morbidity and mortality in endstage renal disease. Journal of the American Society of Nephrology 1996; 7: 728-736.
40. O’Dea DF, Parfrey PS, Harnett JD, Hefferton D, Cramer BC, Green JS. The importance of renal impairment in the natural history of Bardet-Biedl syndrome. American Journal of Kidney Diseases 1996; 27: 776-783.
41. Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE. The impact of anaemia on cardiomyopathy, morbidity and mortality in endstage renal disease. American Journal of Kidney Diseases 1996; 28: 53-61.
42. Foley RN, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE. The impact of hypertension on cardiomyopathy, cardiac morbidity and mortality in chronic uraemia. Kidney International 1996; 49: 1379-1385.
43. Parfrey PS, Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors of ischemic heart disease in chronic uraemia. Kidney International 1996; 49: 1428-1434.
44. Parfrey PS, Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors for left ventricular disorders in chromic uraemia. Nephrology, Dialysis Transplantation 1996; 11: 1277-1285.
45. Armstrong PW, Cairns JA, Carruthers SG, Munt PW, Powell C; for the Canadian Association of Professors of Medicine ( Harnett JD). Canadian academic departments of medicine amid health-care reform. Annals of the Royal College of Physicians and Surgeons of Canada 1997; 30 (5): 279-282.
46. Foley RN, Culleton BF, Parfrey PS, Harnett JD, Kent GM, Murray DC, Barre PE. Cardiac disease in diabetic end-stage renal disease. Diabetologia 1997; 40: 1307-1312.
47. Foley RN, Parfrey PS, Harnett JD,Kent GM, O’Dea R, Murray DC, Barre PE. Mode of dialysis therapy, cardiac morbidity, and mortality in end-stage renal disease. JASN 1998; 9: 267-276.
48. van Ypersele de Strihou C, Brayer M, Fresco C, Harnett JD, Kirsch KA, Nosadini R, Schaefer F, Serjeant GR, Stevens PE, Vanrenterghem Y, Verbeelen D, Watkins PJ. Should anaemia in subtypes of CRF patients be managed differently. Nephro Dial Transplant 1999; 14 [Suppl 2]: 37-45.
49. Reddy ER, Bartlett PJ, Harnett JD, McManamon PJ, Snelgrove C. Telemedicine and fetal ultrasonography in a remote Newfoundland community. CMAJ 2000; 162: 206-7.
50. Elford R, White H, Bowering R, Ghandi A, Maddiggan, St. John K, House M, Harnett JD, West R, Battcock A. A randomized, controlled trial of child psychiatric assessments conducted using videoconferencing. Journal of Telemedicine and Telecare 2000; 6: 73-82.
51. Foley RN, Parfrey PS, Kent GM, Harnett JD, Murray DC, Barre PE. Serial, Changes in Echocardiographic Parameters and Cardiac Failure in End-Stage Renal Disease. Journal of the American Society of Nephrology 2000; 11: 912-916.
52. Furey A, Stone C, Squire D, Harnett J. Os calcis fractures: analysis of interobserver variability using Sanders classification. J Foot Ankle Surg. 2003 Jan-Feb; 42(1):21-3
53. Harnett J, ACP Journal Club Review: Blood pressure-lowering treatments reduce CV morbidity and mortality in Ann. Int. Med. 2009 July, 151(2): JC1-6.
54. Harnett, JD, Neuman R. Research Ethics for Clinical Researchers. Methods Mol Biol 2015 ;1281:19-30
55. Smith N, Harnett J, Furey A. Evaluating the reliability of surgical assessment methods in an orthopedic residency program. Can J Surgery 2015, 58 (4): 010614 – 10614. Epub Aug 1 2015.
BOOKS:
Parfrey PS; Harnett JD. Cardiac dysfunction in chronic uraemia. Kluwer Academic Publishers; Boston 1991; p 320.
BOOK CHAPTERS:
Parfrey PS, Harnett JD. The natural history of left ventricular dysfunction in dialysis patients in "Cardionephrology". Edited by M Timio and V Wizeman. Wichtig Editore Milan 1991; 101-1081.
Parfrey PS, Harnett JD. The natural history of myocardial disease in dialysis patients in "Cardiac Dysfunction in Chronic Uraemia". Edited by PS Parfrey and JD Harnett. Kluwer Academic Publishers; Boston 1992; 39-52.
Harnett JD, Parfrey PS. The management of congestive heart failure in uraemic patients in "Cardiac Dysfunction in Chronic Uraemia". Edited by PS Parfrey and JD Harnett. Kluwer Academic Publishers; Boston 1992; 221-230.
Parfrey PS, Harnett JD. Morbitité et mortalité d’origine cardiaque dans le suivi á long verme des patients dialysés in "Archialités Néphrologiques"; Jean Hamburger; Hospital Necker 1993. Médicine - Sciences; Flammarion; Paris.
Harnett JD, Parfrey; PS. Antihypertensive agents in dialysis patients: blood pressure control and regression of LV hypertrophy in "Cardionephrology". Edited by M. Timi and V. Wizeman. Wichtig Editore 1993 ( in press).
Parfrey PS, Harnett JD. Long-term cardiac morbidity and mortality during dialysis therapy in "Advances in Nephrology". Editors Grunfeld; Bach; Kreis and Maxwell. Mosby; St. Louis; 1994; (23): 311-330.
Harnett JD, Parfrey PS. Blood pressure control and regression of LV hypertrophy in dialysis patients in "Cardiorenal Disease". Editors M. Timio and V. Wizemann. Karger; New York; 1994; (106): 110-113.
Parfrey PS, Harnett JD. Cardiovascular system in uraemia: cardiomyopathy in "Textbook of Nephrology; 3rd Edition". Edited by SG Massey and RJ Glassock. Williams and Wilkins; Baltimore; 1995; 1342-1352.
Harnett JD, Parfrey PS. Left ventricular dysfunction in dialysis patients in "The Principles and Practice of Dialysis". Edited by WL Henrich. Williams and Wilkins; Baltimore; 1994; 170-180.
Parfrey PS, Harnett JD, Green JS. Laurence-Moon-Biedl Syndrome in "The Investigation and Management of Inherited Disorders of the Kidney". Edited by Morgan and JP Grunfield. Oxford University Press; Oxford (in press).
Harnett JD, Parfrey PS. Left ventricular dysfunction in dialysis patients in "The Principles and Practice of Nephrology". Edited by WL Henrich. Williams and Wilkins; Baltimore; Second Edition (in press).
Parfrey PS, Foley RN, Harnett JD. Organ system and metabolic complications in chronic dialysis: cardiac in “Replacement of Renal Function by Dialysis”. Edited by C. Jacobs; CM Kjellstrand; KM Koch; JF Winchester. Kluwer Academic; Boston ; 1996; 990-1002.
Harnett, JD, Neuman R. Research Ethics for Clinical Researchers in “Clinical Epidemiology: Practice and Methods”. Edited by Parfrey, PS and Barrett BJ; Humana Press , New York 2009; 285-298.