Natural Selection, Selective Neutrality, & Genetic Drift in Finite Populations
Theory of
Selective Neutrality
: the
Neutral Equation
Trajectory of a
neutral allele
Replicate trajectories
of
neutral alleles
from f(
B
) =
0.50
Replicate trajectories
of
rare
neutral alleles
from
f(
B
) =
0.01
Fixation of a
rare advantageous
allele
, with
variable
s
with respect to
N
Fate of a
single
novel allele
(
N
=
100
,
2N
=
200
alleles,
f(
B
)
=
0.005
) under
strong positive selection
(
s
=
-0.100
)
weak positive selection
(
s
=
-0.010
)
weak
negative selection
(
s
=
0.010
)
strong negative selection
(
s
=
0.100
)
Fixation of Neutral alleles by selection
"
Selective Sweep
" without recombination
"
Hitchhiking
"
with recombination
Text
material © 20
2
5 by
Steven M Carr