Drift & Fixation of rare
alleles with strong selective
advantage in finite populations
(N =
100, f(B0) = 0.005, W0 = W1
= 0.9, W2 = 1.0)
From a single initial allele (f(B) =
1/200 = 0.005 in N = 100 @) [left],
almost all populations go to f(B) = 0 within
20 generations, despite the selective advantage of the BB
genotype. Five populations, once they reach a threshold
of f(B) > ~0.1, reach f(B) = 1
within 150 generations. Where the same conditions apply to
the A allele [right], compare the
trajectories and range of these stochastic results
with the deterministic expectation [black curve].
Text material
© 2024 by Steven M. Carr