Overdominance: Selection for a favorable heterozygote
Let the fitness of the three phenotypes be WAA
= 0.9, WAa = 1.0,
and Waa = 0.8, such that
the heterozygote has the greatest fitness ("overdominance"). In the
alternative notation, s1 =
0.1 and s2 = 0.2. From any
starting value of fA
at
time t = 0 (e.g., fA
= 0.01 or fA
= 0.99), fA
will converge on an equilibrium
= 0.2 /
(0.1 + 0.2) = 0.67 [NS_07-Box6.html]
such that A and a are both maintained in
the population so as to produce maximum fitness.
HOMEWORK:
In this example, why is
= 0.67 rather than 0.33?
Text material
© 2020 by Steven M. Carr