NS 07-06

Overdominance: Selection for a favorable heterozygote

Let the fitness of the three phenotypes be WAA = 0.9, WAa = 1.0, and Waa = 0.8, such that the heterozygote has the greatest fitness ("overdominance"). In the alternative notation, s1 = 0.1 and s2 = 0.2. From any starting value of fA at time t = 0 (e.g., fA = 0.01 or fA = 0.99), fA will converge on an equilibrium = 0.2 / (0.1 + 0.2) = 0.67 [NS_07-Box6.html] such that A and a are both maintained in the population so as to produce maximum fitness.

HOMEWORK: In this example, why is = 0.67 rather than 0.33?


Text material © 2020 by Steven M. Carr