Mytilus LAP
            gradient

Genetic cline in salinity tolerance of Mytilus edulis mussels

    Leucine Amino Peptidase (LAP) is an enzyme that cleaves peptide bonds adjacent to Leucine residues in proteins. In the Blue Mussel (Mytilus edulis), the electrophoretic allele lap94 at the leucine amino peptidase (lap) locus  produces a form of the enzyme that has been shown experimentally to function best in saline environments. In Long Island Sound east of New York City, there is a strong salinity gradient beginning with freshwater in more westerly locations through increasingly brackish sites eastward (sites 1 8), where salinity reaches nearly the same level as that on the sea-ward side of Long Island (sites 9 11). The frequency of lap94 increases in a cline as a function of local adaptation to local salinity and gene flow between adjacent locations. As with other biochemical adaptations, differences among alleles at the same locus produce different genotypes, which are expressed as different phenotypes that are variably adaptive in different environments.

    Homework: In no more than three sentences, define the differences between the enzyme LAP, the gene locus lap, and the allele
lap94 . Is the allele lap94 part of the genotype or the phenotype?


Text material © 2024 by Steven M. Carr