Conformational
changes of enzymes during catalysis
In
the
uninduced form of the
enzyme
[left], three crucial amino
acid
residues in the active
site are relatively far apart [left]. During induction of enzymatic
activity [right], the
active site residues
shift closer to each other so as to bind the substrate in the enzyme-substrate
complex, as
predicted
by the induced-fit model.
Figure © 2002
by
Griffiths
et
al. ; All
text
material ©2011 by Steven
M.
Carr
