Microsatellite profiles detected by multiplex capillary
electrophoresis
Microsatellites can be fluorescently tagged
with the same dyes used in DNA sequencing. With
13 loci in the CODIS set
spread over three labeling reactions, each with a
separate color [blue,
green & yellow [shown in
black]], all 13 loci can be combined in a single
multiplex experiment [fourth box]. with the
remaining color [red]
used as a size standard [red bands]. Allelic variants at
each locus are identifiable as a particular color over a
particular size range.
Figure ©2012 TA Brown, Introduction
to Genetics (1st ed.); additional
text ©2016 by Steven M. Carr