Ligation of Okazaki fragments during lagging strand DNA synthesis
Extension of DNA
synthesis stops when the 5' end of the RNA
primer is encountered. The exonuclease acitivty
of the DNAPol III removes the primer, DNAPo
lI fills in the gap, and DNA ligase joins
the 3' and 5' ends.
Figure © 2012 TA Brown, Introduction
to Genetics (1st ed.); additional
text © 2014 by Steven M. Carr