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Alternative splicing leads
to different forms of the same protein
The intron
/ exon-equivalent structure of the human dystrophin
gene includes 35 exon-equivalents, of which 8 (those in green) are included or
excluded in various combinations to produce an mRNA that
is translated to make a tissue-specific form of the protein.
The huge number of possible combinations means that the
protein can be fine-tuned for tissue-specific functions.
This also provides a basis for the evolution of new gene
functions