The Hampé Experiment
(A) In reptiles and mammals, the
two paired bones of the distal hind limbs are the tibia and fibula,
which
articulate with the metatarsal bones of the foot through a
series of small
tarsal elements in the ankle. (B) In modern
birds, the tibia is fused with
the tarsal bones as the major limb element
(the tibiotarsus or "drumstick"),
and the fibula has withdrawn from
the ankle articulation and develops only as a small proximal splint.
Hampé (1960)
inserted a thin slip of non-porous mica between the
developing tibia and fibula of an embryonic chick (C). Separated
from the inhibitory
growth field of the tibia, the fibula grew to the same length as the
tibia (D).
The extended fibula also induced re-formation of the metatarsals as
separate
elements from the tibia (E), producing a condition resembling
that
of the bird ancestor Archaeopteryx.