Deamination mutagenesis

(a) Loss of an amine (NH2) group changes C to U, which will pair with A.

(b) Methylation of bases is one form of post-replication modification that marks bases as newly-replicated. Methyl C bases (mC) may undero deamination to T, which will pair with A.


Figure ©2000 by Griffiths et al. ; text ©2024 by Steven M. Carr