The genetic code for leucine
(Leu) can be either CUN
or UUR. Consequently, either
UUA or CUA or UUG
or CUG (YUA or YUG)
code for Leu. That is, these first codon
position changes do not alter the amino acid, and are the only
exceptions to the rule that first positions 'always' lead
to amino acid substitutions in the Universal Code.
Homework:
There are two other amino acids encoded by six codons
each: find the, and explain why they don't violate the rule.