Alternative Modes
DNA
replication:
Semiconservative,
Conservative, & Dispersive
The Meselsohn-Stahl experiment used
density gradient centrigugation to
follow the behavior of newly-synthesized DNA strands. The results
are
shown on the right, in a figure taken from the original 1958
paper.
Homework:
The diagrams show the
alternative "conservative"
and "dispersive" models,
and the actual
results.
(1)
Explain how the data support the semi-conservative
model.
(2)
At which
stage is it possible to
eliminate
the alternative Conservative and Dispersive models of
replication?
Explain.
Figure ©
2004 by
Griffiths et al. ;
text © 2011 by Steven M.
Carr