In the presence of inbreeding to the extent F, the frequency of homozygotes increases, and the frequency of heterozygotes decreases, as:
f(AA) = (1 - F)(p2)
+ Fp
f(AB) = (1 - F)(2pq)
f(BB) = (1 -
F)(q2) + Fq
HOMEWORK: Show
that the increased frequency of AA & BB
homozygotes equals the decreased frequency of AB
heterozygotes.
Show that
the allele frequencies f(A) and f(B)
are unchanged by inbreeding.